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Aim:  Carbapenems are antibiotics reserved for treatment of severe infections. Carbapenem antimicrobial susceptibility testing profiles were determined in a population of  Klebsiella pneumoniae , and their resistance assessed based on previous and current Clinical and Laboratory Standards Institute criteria.    Materials & methods:  Isolates were examined using an automated antimicrobial susceptibility testing method, and real time polymerase chain reaction to detect the resistance ( blaKPC ) gene.    Results:  The prevalence of  blaKPC  gene was 45/54 (83.3%). Five isolates that were susceptible under the previous criteria changed to nonsusceptible with the current standards. The overall difference in susceptibility between the standards was 8%.    Conclusion:  This study shows that the current Clinical and Laboratory Standards Institute criteria may not offer additional benefits in the fight against carbapenem-resistant  Enterobacteriaceae .

Comparison of Clinical & Laboratory Standards Institute standards in antimicrobial susceptibility among the carbapenemase producing Enterobacteriaceae