Open AccessGold nanoparticles to improve HIV drug delivery
Author(s) -
Carolina Garrido,
C.J.S.M. Simpson,
Noelle P. Dahl,
Jamee Bresee,
Daniel C. Whitehead,
Erick A. Lindsey,
Tyler Harris,
Candice A. Smith,
Carly J. Carter,
Daniel L. Feldheim,
Christian Melander,
David M. Margolis
Publication year - 2015
Publication title -
future medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.708
H-Index - 69
eISSN - 1756-8927
pISSN - 1756-8919
DOI - 10.4155/fmc.15.57
Subject(s) - drug delivery , human immunodeficiency virus (hiv) , drug , nanotechnology , colloidal gold , nanoparticle , drug discovery , targeted drug delivery , pharmacology , medicine , virology , chemistry , materials science , biochemistry
Antiretroviral therapy (ART) has improved lifespan and quality of life of patients infected with the HIV-1. However, ART has several potential limitations, including the development of drug resistance and suboptimal penetration to selected anatomic compartments. Improving the delivery of antiretroviral molecules could overcome several of the limitations of current ART.