Open AccessInvestigation of the protective effect of thymoquinone of U87 cells induced by beta-amyloid
Author(s) -
Gülüzar Özbolat,
Ares Alizade
Publication year - 2021
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2021_120
Subject(s) - thymoquinone , superoxide dismutase , chemistry , antioxidant , apoptosis , cell culture , pharmacology , catalase , amyloid beta , caspase 3 , microbiology and biotechnology , biochemistry , programmed cell death , medicine , biology , peptide , genetics
Thymoquinone (TQ) is the active compound extracted from Nigella sativa which has been reported to possess various pharmacological attributes. This study shows that Thymoquinone (TQ) is an Alzheimer's disease (AD) model cell line on amyloid-beta (Aβ) -induced U87 (human astrocytoma cell line) in β-amyloid (Aβ)-induced in vitro Alzheimer's Disease (AD) model.