Open AccessThe role of miRNAs targeting K-ras and APC genes in colorectal cancer
Author(s) -
Nimet Yılmaz,
Ümit Yılmaz,
K Tanbek,
Soykan Arıkan,
Nihat Aksakal,
U Zeybek,
Arzu Ergen
Publication year - 2020
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2020_092
Subject(s) - microrna , oncogene , carcinogenesis , colorectal cancer , cancer , biology , cancer research , gene , medicine , genetics , cell cycle
The occurrence of abnormal expression patterns in different types of cancer suggests that micro RNAs (miRNAs) may play an important role in tumorigenesis. The aim of this study was to examine the expression levels of miRNAs known to be associated with the regulation of the expression levels of the APC and K-ras, which are important in the development of colorectal cancer (CRC).