Open AccessIL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia
Author(s) -
Gamze Güney Eskiler,
Erhan Bezdegümeli,
Zeynep Özman,
Atilla Özkan,
Cemil Bilir,
Bilge Nur Küçükakça,
Merve İnce,
Angela Men,
Ozge Nur Aktaş,
Y E Horoz,
Deniz Akpınar,
İpek Genç,
Süleyman Kaleli
Publication year - 2019
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2019_136
Subject(s) - cachexia , breast cancer , medicine , cancer , lung cancer , stat3 , oncology , gastroenterology , cancer research , signal transduction , biology , biochemistry
We investigated the changes in the IL-6 and STAT3 expression levels in cachectic and non-cachectic patients with gastric, lung and breast cancer and evaluated the association between IL-6 and STAT3 levels and cancer types in terms of cachexia condition.