IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia
Author(s) -
Gamze Güney Eskiler,
Erhan BEZDEGÜMELİ,
Zeynep Özman,
Asuman Deveci Özkan,
Cemil Bilir,
Bilge Nur Küçükakça,
Merve İnce,
Angela Men,
O. Aktas,
Y. E. Horoz,
Denizhan Akpınar,
İpek Genç,
Süleyman Kaleli
Publication year - 2019
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2019_136
Subject(s) - cachexia , breast cancer , medicine , cancer , lung cancer , stat3 , oncology , gastroenterology , cancer research , signal transduction , biology , biochemistry
We investigated the changes in the IL-6 and STAT3 expression levels in cachectic and non-cachectic patients with gastric, lung and breast cancer and evaluated the association between IL-6 and STAT3 levels and cancer types in terms of cachexia condition.
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