Open AccessThe role of kisspeptin on aromatase expression in breast cancer
Author(s) -
Mehmet Yılmaz,
Hüseyın Öksüz,
Nermin Seda Ilgaz,
IT Ocal,
Mostafa Norizadeh Tazehkand
Publication year - 2019
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2018_141
Subject(s) - kisspeptin , skbr3 , aromatase , endocrinology , medicine , estrogen receptor , biology , cancer research , breast cancer , estrogen , receptor , cancer , hormone , human breast
Kisspeptin is a reproductive peptide hormone that has anti-metastatic roles in several cancer types including colon, lung, and brain cancer. However, in breast cancer, increasing of kisspeptin expression induces aggressiveness of tumors, which in turn exacerbates breast cancer prognosis.