Open AccessDetermination of CEBPA mutations by next generation sequencing in pediatric acute leukemia
Author(s) -
DF Akın,
DA Öner,
Emin Kürekçi,
Nejat Akar
Publication year - 2018
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2018_068
Subject(s) - cebpa , kras , missense mutation , npm1 , mutation , biology , cancer research , gene , leukemia , genetics , medicine , karyotype , chromosome
The CCAAT/enhancer-binding protein-alpha (CEBPA) is lineage-specific transcription factor in the hematopoietic system. In this study, we aimed on the clinical features and the prognostic significance associated with CEBPA mutations in 30 pediatric patients with acute leukemia.