Open AccessDecreased circulatory microRNA-4478 as a specific biomarker for diagnosing non-ST-segment elevation myocardial infarction (NSTEMI) and its association with soluble leptin receptor
Author(s) -
R. Gholikhani-Darbroud,
Fatemeh KhakiKhatibi,
Fatemeh Mansouri,
M. Hajahmadipoorrafsanjani,
Morteza Ghojazadeh
Publication year - 2017
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2017_129
Subject(s) - biomarker , myocardial infarction , medicine , endocrinology , biology , biochemistry
This study aimed to assess the usefulness of circulatory microRNA-4478 (miR-4478) and soluble leptin receptor (sLEPR) in prognosis and diagnosis of non-ST-segment elevation myocardial infarction (NSTEMI) and to introduce miR-4478 as a new biomarker for NSTEMI disease. This study aimed also to examine correlation between miR-4478 and soluble leptin receptor and effects of miR-4478 on leptin receptor concentration.