Association of angiogenic cytokines (VEGF-A and VEGF-C) and clinical characteristic in women with unexplained recurrent miscarriage | Zendy

Ali Bagheri | Zendy; Pratap Kumar | Zendy; Ajay Kamath Nileshwar | Zendy; Pragna Rao | Zendy

Open Access

Association of angiogenic cytokines (VEGF-A and VEGF-C) and clinical characteristic in women with unexplained recurrent miscarriage

Author(s) -

Ali Bagheri,

Pratap Kumar,

Ajay Kamath Nileshwar,

Pragna Rao

Publication year - 2017

Publication title -

bratislavské lekárske listy/bratislava medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 32

eISSN - 1336-0345

pISSN - 0006-9248

DOI - 10.4149/bll_2017_051

Subject(s) - miscarriage , medicine , vascular endothelial growth factor , angiogenesis , abortion , pregnancy , recurrent miscarriage , vegf receptors , gestation , obstetrics , gynecology , gastroenterology , biology , genetics

Recurrent miscarriage (RM) defined as 2 or more spontaneous miscarriage before 20 weeks of gestation, affects at least 1 % of couples trying to conceive. In over 50 % of cases, the cause of the loss of pregnancy remains unexplained. Reduced expression of Angiogenic factors such as: vascular endothelial growth factor (VEGF-A) and VEGF-C has been linked with spontaneous miscarriage, likely due to defective foetal and placental angiogenesis.

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