Open AccessCeliac disease and dysfunctional uterine bleeding; the efficiency of gluten free diet
Author(s) -
Mohammad Javad Ehsani-Ardakani,
M Fallahian,
Kamran Rostami,
Mohammad RostamiNejad,
Saeid Reza Lotfi,
Hamid Mohaghegh Shalmani,
Reza Dabiri,
Mohsen Norouzinia,
F Azizpour-Shoobi,
Mohammad Reza Zali
Publication year - 2014
Publication title -
bratislavské lekárske listy/bratislava medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 32
eISSN - 1336-0345
pISSN - 0006-9248
DOI - 10.4149/bll_2014_004
Subject(s) - dysfunctional uterine bleeding , medicine , dysfunctional family , disease , gluten free , gluten , sprue , family history , pediatrics , gynecology , gastroenterology , obstetrics , psychiatry , endometrium , pathology , mold , biology , genetics
The aim of this study was to investigate the relation between Celiac disease (CD) and unexplained dysfunctional uterine bleeding (DUB) in celiac women. The celiac patients were selected from women who were referred to celiac department. Controls were selected from those women without any signs of celiac disease and matched with age. Meanwhile, a trained physician was ready to explain the study, and then in case of their allowance, a questionnaire was completed by the physician. 24 % of celiac women reported a past history of at least one menstrual cycle disorder vs 10 % of controls reported these problems (p=0.038) and higher percentage of unexplained DUB has been observed in celiac women. All celiac patients were undertaking gluten free diet for at least 3 months and the celiac patients who reported the history of DUB were again interviewed for any signs of unexplained DUB. From 12 celiac women with DUB, 10 patients reported no more unexplained DUB after getting gluten-free diet (83.3 %). The occurrence of a significant correlation between CD and DUB suggests the possibility of considering CD as one of the potential causes of abnormal uterine bleeding. Therefore, celiac disease must be seriously considered in the screening of patients with reproductive disorders (Tab. 2,Ref. 23).