Open AccessCan gallium-68 prostate-specific membrane antigen ligand be a potential radiotracer for renal cortical positron emission tomography imaging?
Author(s) -
İsmet Sarıkaya,
Abdelhamid H. Elgazzar,
Mahmoud Alfeeli,
Ali Sarıkaya
Publication year - 2018
Publication title -
world journal of nuclear medicine
Language(s) - English
Resource type - Journals
eISSN - 1607-3312
pISSN - 1450-1147
DOI - 10.4103/wjnm.wjnm_35_17
Subject(s) - medicine , positron emission tomography , prostate cancer , glutamate carboxypeptidase ii , ligand (biochemistry) , parenchyma , gallium , nuclear medicine , kidney , prostate , positron , pathology , cancer , receptor , chemistry , physics , organic chemistry , quantum mechanics , electron
Gallium-68 prostate-specific membrane antigen (Ga-68 PSMA) ligand (HBED-CC) is a new promising positron emission tomography (PET) tracer for prostate cancer. Intense renal parenchymal uptake is a physiologic finding on Ga-68 PSMA ligand PET images. Evaluation of kidneys in low intensity demonstrates excellent distribution of this radiotracer in renal parenchyma with excellent image quality and resolution. In this article, we present the Ga-68 PSMA ligand PET renal images of four patients with prostate cancer. In two patients, there is normal distribution of radiotracer, and in other two, there are renal cysts causing parenchymal defects.