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Incidental detection of asymptomatic brain metastases on 18F-fluoride positron emission tomography/computed tomography and 68Ga DOTANOC positron emission tomography/computed tomography in a patient with concomitant breast carcinoma and a pancreatic neuroendocrine tumor
Author(s) -
Ruth Brown,
Phei Shan Chuah,
Emmanouil Panagiotidis,
Sobhan Vinjamuri
Publication year - 2018
Publication title -
world journal of nuclear medicine
Language(s) - English
Resource type - Journals
eISSN - 1607-3312
pISSN - 1450-1147
DOI - 10.4103/wjnm.wjnm_10_17
Subject(s) - medicine , positron emission tomography , positron emission tomography computed tomography , somatostatin receptor , magnetic resonance imaging , radiology , tomography , positron emission , breast cancer , asymptomatic , nuclear medicine , concomitant , cancer , pathology , somatostatin
A 54-year-old female treated for locally advanced ductal breast carcinoma was also diagnosed with a pancreatic neuroendocrine tumour. A staging 68 Ga DOTANOC positron emission tomography/computed tomography (PET/CT) demonstrated somatostatin receptor-positive foci within the brain parenchyma. A whole body 18 F-fluoride PET/CT also demonstrated several foci of low-grade tracer uptake in the brain. Magnetic resonance imaging confirmed several cerebral and cerebellar metastases. This case highlights the need to be aware of each tumor's metastatic profile and the careful attention required for thoroughly evaluating imaging in the presence of multiple pathologies. Furthermore, such incidental findings can have significant treatment and prognostic implications.

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