Open AccessPhenotypic profile of pulmonary aspergillosis and associated cellular immunity among people living with human immunodeficiency virus in Maiduguri, Nigeria
Author(s) -
Idris Nasir Abdullahi,
Halima Ali Shuwa,
Anthony Uchenna Emeribe,
Hafeez Aderinsayo Adekola,
Amos Dangana
Publication year - 2019
Publication title -
tzu-chi medical journal/cí-jì yīxué
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.343
H-Index - 15
eISSN - 2223-8956
pISSN - 1016-3190
DOI - 10.4103/tcmj.tcmj_46_18
Subject(s) - medicine , aspergillosis , immunity , immunology , human immunodeficiency virus (hiv) , phenotype , virology , cellular immunity , virus , immunodeficiency , immune system , biology , gene , biochemistry
Aspergillus causes many forms of pulmonary infectious diseases ranging from colonization (noninvasive) to invasive aspergillosis. This largely depends on the underlying host's lung health and immune status. Pulmonary aspergillosis (PA), especially the invasive form, occurs as opportunistic to human immunodeficiency virus (HIV) as a result of cluster of differentiation (CD)4+ lymphopenia. The majority of patients with comorbid HIV and aspergillosis go undiagnosed. This study aimed to isolate, identify the etiologies, and determine the prevalence of PA among HIV-infected persons with a productive cough (at least <2 weeks) at the HIV Clinics of the University of Maiduguri Teaching Hospital, Nigeria.