Open AccessMolecular characterization of colorectal cancer: A five-gene prognostic signature based on RNA-binding proteins
Author(s) -
Qian-Kun Liang,
Xiaojuan Du,
Lanfang Mao,
Guopan Wang
Publication year - 2021
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/sjg.sjg_530_20
Subject(s) - rna binding protein , biology , cancer research , gene , gene expression , rna , microbiology and biotechnology , medicine , genetics
Colorectal cancer (CRC) is one of the most common cancers worldwide. RNA-binding proteins (RBPs) regulate essential biological processes and play essential roles in a variety of cancers. The present study screened differentially expressed RBPs, analyzed their function and constructed a prognostic model to predict the overall survival of patients with CRC.