Open AccessSuccessful response of intradermal hepatitis B vaccine in nonresponders of intramuscular hepatitis B vaccine in general and hemodialysis population
Author(s) -
Farina Hanif,
Nasir Mehmood,
Zain Majid,
Nasir Hassan Luck,
Syed Mudassir Laeeq,
Abbas Ali Tasneem,
Muhammad Manzoor Ul Haque
Publication year - 2020
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/sjg.sjg_300_20
Subject(s) - medicine , hemodialysis , vaccination , population , hepatitis b , hepatitis b vaccine , hepatitis b virus , immunology , titer , gastroenterology , antibody , virus , hbsag , environmental health
Hepatitis B infection is one of the most common infections worldwide, with its vaccination being an effective preventive measure. Nonresponse to hepatitis B vaccination increases population susceptibility to virus dissemination along with detrimental complications. Despite twice intramuscular vaccination series, 14.3% in the general population and 50% in hemodialysis patients fail to mount a response against hepatitis B. We aimed to evaluate the effectiveness of intradermal (ID) vaccination in the nonresponders amongst the general and hemodialysis population.