Open AccessPresence of pink-color sign within 1 min after iodine staining has high diagnostic accordance rate for esophageal high-grade intraepithelial neoplasia/invasive cancer
Author(s) -
Jia-Yao Zheng,
Ya-Hua Chen,
Yangyang Chen,
Xiaojiao Zheng,
Shishun Zhong,
Wanyin Deng,
Jianming Zheng,
Xianbin Guo,
Lei Gao,
Wei Liang
Publication year - 2019
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/sjg.sjg_274_18
Subject(s) - chromoendoscopy , medicine , intraepithelial neoplasia , esophageal cancer , histopathology , gastroenterology , lesion , receiver operating characteristic , staining , pathology , cancer , colorectal cancer , prostate , colonoscopy
The dramatic color change after iodine staining (from white-yellow to pink after 2-3 min), designated as the "pink-color sign" (PCS), is indicative of esophageal high-grade intraepithelial neoplasia (HGIN) or an invasive lesion. However, no study has yet examined the association between the time of PCS appearance and histopathology. We investigated the association between the time of PCS appearance and esophageal histopathology in 456 lesions of 438 patients who were examined for suspected esophageal cancer.