Open AccessClinical trials during the COVID-19 pandemic: Challenges of putting scientific and ethical principles into practice
Author(s) -
Arun Bhatt
Publication year - 2020
Publication title -
perspectives in clinical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.649
H-Index - 8
eISSN - 2229-5488
pISSN - 2229-3485
DOI - 10.4103/picr.picr_77_20
Subject(s) - pandemic , covid-19 , clinical trial , informed consent , engineering ethics , medicine , clinical practice , research ethics , alternative medicine , family medicine , outbreak , virology , pathology , engineering , disease , infectious disease (medical specialty)
Global pandemic of COVID-19 is a serious unmet medical need requiring clinical research into effective therapies. Clinical trials during pandemics of infections face complex challenges of putting scientific and ethical principles into practice. Some of these issues - selection of investigational product and participants, study design, assessment of efficacy and safety, ethics review, informed consent and publication, sample size, and publications - require in-depth consideration in planning and implementation of clinical trials during pandemics.