Open AccessA study of harmful drug–drug interactions due to polypharmacy in hospitalized patients in Goa Medical College
Author(s) -
Akshay Khandeparkar,
Padmanabh V. Rataboli
Publication year - 2017
Publication title -
perspectives in clinical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.649
H-Index - 8
eISSN - 2229-5488
pISSN - 2229-3485
DOI - 10.4103/picr.picr_132_16
Subject(s) - polypharmacy , medicine , drug , medical prescription , concomitant , observational study , adverse effect , pharmacotherapy , pharmacology , drug interaction
Concomitant use of multiple drugs is often indicated to manage comorbid conditions and enhance efficacy. Such concomitant use of multiple drugs (five or more drugs) has been defined as "polypharmacy." Polypharmacy has been associated with adverse consequences such as greater healthcare costs, increased risk of adverse drug events, drug-drug interactions (DDIs), medication nonadherence, reduced functional capacity, and multiple geriatric syndromes. This study evaluated number of potential harmful DDIs due to polypharmacy.