Open AccessA Clinico-Microbiological Study of Prosthetic Joint Infections in an Indian Tertiary Care Hospital: Role of Universal 16S rRNA Gene Polymerase Chain Reaction and Sequencing in Diagnosis
Author(s) -
Sujeesh Sebastian,
Rajesh Malhotra,
Vishnubhatla Sreenivas,
Arti Kapil,
Rama Chaudhry,
Benu Dhawan
Publication year - 2019
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.4103/ortho.ijortho_551_18
Subject(s) - medicine , polymerase chain reaction , tertiary care , 16s ribosomal rna , ribosomal rna , gene , bioinformatics , genetics , surgery , biology
We determined the magnitude and clinico-microbiological profile of prosthetic joint infection (PJI) at a tertiary hospital. The diagnostic potential of 16S rRNA gene polymerase chain reaction (PCR) and sequencing on periprosthetic tissue samples was evaluated for the diagnosis of PJI.