Open AccessEffectiveness and Safety of the Combined Use of Tranexamic Acid: A Comparative Observational Study of 1909 Cases
Author(s) -
Charles-Hervé Vacheron,
Pascal Roy,
P Petit,
James Appery,
Michel Henri Fessy,
Vincent Piriou,
Anthony Viste,
Arnaud Friggeri
Publication year - 2019
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.4103/ortho.ijortho_148_19
Subject(s) - medicine , tranexamic acid , confidence interval , hazard ratio , antifibrinolytic , surgery , hemoglobin , observational study , anesthesia , blood transfusion , blood loss
Tranexamic acid (TA) use in lower-limb arthroplasty has been valued in these surgeries high-risk hemorrhagic due to its antifibrinolytic action. The objective of the present study was to determine the effectiveness of the combined intravenous (IV) and intraarticular (IA) administration of TA in lower-limb arthroplasty.