Open AccessTreatment of unilateral zone I cytomegalovirus retinitis in acute lymphoblastic leukemia with oral valganciclovir and intravitreal ganciclovir
Author(s) -
Koushik Tripathy,
Kanhaiya Mittal,
Pradeep Venkatesh,
Sameer Bakhshi,
Rohan Chawla
Publication year - 2017
Publication title -
oman journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 16
eISSN - 0974-7842
pISSN - 0974-620X
DOI - 10.4103/ojo.ojo_190_2016
Subject(s) - valganciclovir , ganciclovir , medicine , cytomegalovirus retinitis , retinitis , cytomegalovirus , leukemia , foscarnet , pediatrics , immunology , human cytomegalovirus , human immunodeficiency virus (hiv) , virus , herpesviridae , viral disease
Cytomegalovirus retinitis (CMVR) is an opportunistic infection seen in immunocompromised patients, especially suffering from acquired immune deficiency syndrome. It is uncommonly seen in hematological malignancies and in patients on immunosuppressants. The authors present a 12-year-old girl with unilateral CMVR who was on maintenance phase therapy for mixed phenotype (B/myeloid) leukemia. Serology for human immunodeficiency virus was negative. The child was successfully treated with oral valganciclovir and repeated intravitreal ganciclovir injections. CMVR in pediatric population with leukemia can be successfully treated with oral valganciclovir and intravitreal ganciclovir injections.