Open AccessSpontaneously resolved severe retinopathy associated with aplastic anemia
Author(s) -
Washoo Mal,
Mohammed Al Abri
Publication year - 2021
Publication title -
oman journal of ophthalmology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 16
eISSN - 0974-7842
pISSN - 0974-620X
DOI - 10.4103/ojo.ojo_117_21
Subject(s) - medicine , pancytopenia , aplastic anemia , anemia , retinopathy , spherocytosis , bone marrow , surgery , pathology , splenectomy , spleen , diabetes mellitus , endocrinology
Aplastic anemia is a rare, usually autoimmune disorder of bone marrow stem cells leading to pancytopenia and hypoplastic marrow that presents with anemia, infection or bleeding which can be potentially sight and life-threatening. Patients with aplastic anemia may present with various ocular manifestations; lid and orbital hematoma, sub-conjunctival hemorrhage, sudden visual loss due to vitreous hemorrhage or retinopathy and optic disc edema. A young male patient had symptomatic sever bilateral hemorrhagic retinopathy secondary to aplastic anemia; succeeding systemic allogenic hematopoietic stem-cell transplantation showed almost complete spontaneous resolution of the retinopathy and significant improvement in vision over a period of 16 weeks.