Open AccessRosai–Dorfman disease with isolated lacrimal gland enlargement
Author(s) -
Marian Pauly,
Mekhla Naik,
Subramanian Krishnakumar,
Giridhar Anantharaman
Publication year - 2018
Publication title -
oman journal of ophthalmology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 16
eISSN - 0974-7842
pISSN - 0974-620X
DOI - 10.4103/ojo.ojo_110_2016
Subject(s) - lacrimal gland , medicine , disease , pathology , rosai–dorfman disease , anatomy
Rosai-Dorfman Disease also called as Sinus Histiocytosis with Massive Lymphadenopathy is a rare, benign, idiopathic histiocytic proliferative disorder that occurs predominantly in children and young adults. Orbital involvement can occur in 11% of cases. Isolated lacrimal gland involvement without any local or systemic recurrence is very rare. To the best of our knowledge, only seven cases have been reported in the literature till date. Histopathological and immunohistochemical confirmation is essential in establishing the diagnosis. A benign course is usual, but in some cases, blindness or even fatality may result. We report a case of 30-year-old female with isolated lacrimal gland involvement and 19 months' follow-up.