Open AccessEffect of platelet-rich fibrin versus chitosan-based Axiostat hemostatic agent following dental extraction in cardiac patients on antiplatelet therapy: A comparative study
Author(s) -
K Rajendra,
Swetha Vempalli,
Mithileswer Kadiyala,
Vidushi Sharma,
Swetha Karipineni,
Srikanth Gunturu,
Dipak Baliram Patil
Publication year - 2021
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/njms.njms_270_20
Subject(s) - medicine , hemostasis , platelet rich fibrin , fibrin , wound healing , platelet rich plasma , platelet , chitosan , bleeding time , anesthesia , surgery , platelet aggregation , biochemistry , chemistry , immunology
Platelet-rich fibrin (PRF) is a biomaterial that promotes wound healing. It has a fibrinous matrix wherein platelets, pro-inflammatory cytokines, and various growth factors along with few cells are entrapped while Chitosan is a naturally occurring cationic biopolymeric material that is derived from an animal product, chitin. It has demonstrated biological properties which include acceleration in wound healing, hemostasis, enhancement of immunological response, mucosal adhesion by eliciting biological responses, and anti-microbial action.