Open AccessElectrophysiological evaluation of fleck retina and temporal macular thinning in X-Linked alport's syndrome
Author(s) -
Adel Al Akeely,
Patrik Schatz,
Amro Alhazimi
Publication year - 2021
Publication title -
middle east african journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.357
H-Index - 25
eISSN - 0975-1599
pISSN - 0974-9233
DOI - 10.4103/meajo.meajo_7_21
Subject(s) - photopic vision , medicine , ophthalmology , scotopic vision , retina , fundus (uterus) , erg , optical coherence tomography , electroretinography , visual acuity , retinal , optics , physics
We report a 39-year-old with Alport's syndrome. The patient presented with anterior lenticonus, cataract, and a corrected distance visual acuity of 20/25 and 20/60 in the right and left eyes, respectively. Fundus examination revealed generalized retinal flecks sparing the fovea in both eyes. Optical coherence topography showed temporal macular thinning. Normal fundus autofluorescence was observed in both eyes. Full-field electroretinography (ERG) demonstrated normal photopic and scotopic responses, while multifocal ERG showed no reduction of amplitudes generated from the temporal thinned macula, compared to the nasal macula, indicating preserved functional integrity of the retina.