Open AccessIris melanoma in a child simulating juvenile xanthogranuloma
Author(s) -
Jerry A. Shields,
Carol L. Shields,
Sara E. Lally,
Tatyana Milman,
Ralph C. Eagle
Publication year - 2018
Publication title -
middle east african journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.357
H-Index - 25
eISSN - 0975-1599
pISSN - 0974-9233
DOI - 10.4103/meajo.meajo_7_18
Subject(s) - juvenile xanthogranuloma , medicine , iris (biosensor) , histopathology , pathology , melanoma , biopsy , amelanotic melanoma , dermatology , histiocyte , computer security , cancer research , computer science , biometrics
An 8-year-old girl was referred for an amelanotic iris tumor believed to have enlarged slightly over 3 months, suspicious for juvenile xanthogranuloma (JXG). The affected right eye had a lightly pigmented, vascular iris mass measuring 6 mm in basal dimension and 2 mm in thickness. There were no feeder vessels, seeding, inflammatory cells, or cutaneous abnormalities. Diagnostic fine needle aspiration biopsy (FNAB) was performed, revealing spindle B melanoma cells that were immunoreactive for melanocytic markers HMB45 and Melan-A. Complete tumor resection by basal sector iridectomy was performed. Histopathology confirmed spindle B melanoma. At 14-years follow up, there has been no recurrence or metastasis and visual acuity remains 20/25. Iris melanoma can develop in children and clinically resemble nodular JXG.