Open AccessRespiratory infections: Role of Vitamin D and surfactant proteins A and D
Author(s) -
Rachel Poorna,
Niranjan Biswal
Publication year - 2020
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/lungindia.lungindia_369_18
Subject(s) - vitamin d and neurology , medicine , immune system , inflammation , immunology , vitamin , respiratory tract , lung , mucus , pneumonia , phagocytosis , vitamin d deficiency , respiratory system , microbiology and biotechnology , biology , ecology
Respiratory tract infection is the common viral infection and the principal cause of death among children under 5 years of age. It damages lung epithelium and increases mucus production and inflammation, leading to dyspnea. The sunshine vitamin (Vitamin D) and surfactant protein (SP) A and D along with their usual function play an important role in host defense. This article reviews with immune role of Vitamin D and SP A and D which aids excessive cytokines production, boosts phagocytosis, hinders inflammatory activity, and thus acts as a first-line defense against lung pathogens.