Open AccessPerformance of cytology, acid-fast bacilli smear, gene Xpert and mycobacterial cultures in endobronchial ultrasound-transbronchial needle aspiration aspirate in diagnosing mediastinal tuberculous lymphadenitis
Author(s) -
Venugopal Mohan,
Vivek Nangia,
Anoop Singh,
Rahul Behl,
Nitin Dumeer
Publication year - 2021
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/lungindia.lungindia_128_20
Subject(s) - medicine , mediastinal lymphadenopathy , cytology , radiology , fine needle aspiration , genexpert mtb/rif , tuberculosis , tuberculous lymphadenitis , biopsy , mediastinoscopy , lymph node , mycobacterium tuberculosis , pathology
Diagnosis of isolated mediastinal tuberculosis (TB) can be challenging. Endobronchial ultrasound (EBUS) increases the diagnostic yield by direct sonographic visualization of mediastinal and hilar lymph nodes. With the advent of molecular techniques such as Gene Xpert, their addition to the cytology and cultures increases the diagnostic yield and detection of rifampicin resistance (RR) which helps change the effective therapeutic regimen immediately.