Open AccessRelationship of asymmetric dimethylarginine levels with disease severity and pulmonary hypertension in chronic obstructive pulmonary disease
Author(s) -
Elif Torun Parmaksız,
Ali̇ İnal,
Banu Salepçi,
Sevda Şener Cömert,
Ali Fidan,
Nesrin Kıral,
Coşkun Doğan,
Benan Çağlayan
Publication year - 2018
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/lungindia.lungindia_11_17
Subject(s) - asymmetric dimethylarginine , medicine , copd , pulmonary disease , pulmonary hypertension , cardiology , arginine , endothelial dysfunction , pulmonary function testing , gastroenterology , amino acid , biochemistry , chemistry
Asymmetric dimethylarginine (ADMA) has emerged as a risk marker for many conditions related to pulmonary hypertension (PH); however, little is known about ADMA and symmetric dimethylarginine (SDMA) plasma concentrations in chronic obstructive pulmonary disease (COPD). Our interest centers on the role of ADMA in regulation of endothelial function in COPD and secondary PH. The aim of the present study was to evaluate the serum ADMA, SDMA, and L-arginine concentrations in COPD and its association with PH.