Open AccessThiamine for prevention of postoperative delirium in patients undergoing gastrointestinal surgery: A randomized clinical trial
Author(s) -
Rohollah Moslemi,
Hossein Khalili,
Mostafa Mohammadi,
Zeinab Mehrabi,
Niayesh Mohebbi
Publication year - 2020
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/jrpp.jrpp_19_124
Subject(s) - medicine , delirium , thiamine , randomized controlled trial , odds ratio , adverse effect , emergence delirium , intensive care unit , anesthesia , placebo , surgery , intensive care medicine , alternative medicine , pathology
Postoperative delirium is a common complication after gastrointestinal surgery that is associated with adverse outcomes. Thiamine is an essential cofactor for the glycolysis, oxidative metabolism, production of neurotransmitters in the crebs cycle. In this study, efficacy of thiamine was assessed as a preventive strategy of delirium in patients undergoing gastrointestinal surgery.