Open AccessCiprofloxacin use in hospitalized children: Approved or off-label?
Author(s) -
Toktam Faghihi,
Leila Yavari Tekmehdash,
Mohammad Hadi Radfar,
Kheirollah Gholami
Publication year - 2017
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/jrpp.jrpp_17_27
Subject(s) - medicine , ciprofloxacin , medical prescription , pediatrics , antimicrobial stewardship , antimicrobial , antibiotics , intensive care medicine , pharmacology , antibiotic resistance , chemistry , organic chemistry , microbiology and biotechnology , biology
Fluoroquinolones are not routinely used as the first-line antimicrobial therapy in pediatrics. The American Academy of Pediatrics (AAP) and the United States Food and Drug Administration (FDA) approved fluoroquinolones on certain indications in children. The aim of this study was to evaluate to what extent and how ciprofloxacin is used on approved indication or as off-label. Besides, dose adequacy and treatment duration were assessed.