Open AccessGenome-wide association study in craniosynostosis condition using innovative systematic bioinformatic analysis tools and techniques: Future prospective and clinical practice
Author(s) -
Mayadhar Barik,
Minu Bajpai,
Arun Malhotra,
Jyotish Chandra Samantaray,
Dwivedi Sn,
Sambhunath Das
Publication year - 2018
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/jpn.jpn_71_17
Subject(s) - medicine , craniosynostosis , microcephaly , plagiocephaly , craniofacial , pediatrics , bioinformatics , surgery , psychiatry , biology
Craniosynostosis (CS) conditions are included with the premature fusion of one or more multiple cranial sutures. As the second leading and most common craniofacial anomaly and orofacial clefts globally. Syndromic and nonsyndromic CS (NSCS) occur as a part of a genetic syndrome unlike Apert, Crouzon, Pfeiffer, Muenke, and Saethre-Chotzen syndromes. Approximately, 90% of the cases of CS arises from NSCS group and it is now a great challenge for the researcher and neurosurgeon for Indian-origin children, a great burden worldwide.