Open AccessOrganophosphorus-induced toxic myeloneuropathy: Series of three adolescent patients with short review
Author(s) -
Priyabrata Nayak,
Ayaz Khurram Mallick,
Subhankar Mishra,
Debasish Panigrahy
Publication year - 2019
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/jpn.jpn_45_18
Subject(s) - medicine , myelopathy , neurotoxicity , nervous system , peripheral nervous system , organophosphate , central nervous system , organophosphate poisoning , pediatrics , anesthesia , toxicity , spinal cord , psychiatry , pesticide , agronomy , biology
Organophosphate (OP) poisoning is the most common poisoning in India, accounting for almost half of the hospital admissions due to poisoning. Delayed neuropathy is initiated by an attack on a nervous tissue esterase. Although uncommon, delayed neurotoxicity has been consistently reported in literature. This mechanism is implicated not only in damaging peripheral nervous system but also in causing central processes leading to myelopathy. We report a series of three adolescent patients who came to our hospital with delayed neurological manifestations of organophosphorus poisoning, which came out to be OP-induced myeloneuropathy after detailed analysis and evaluation.