Open AccessEmphysematous osteomyelitis caused by Salmonella typhi in beta thalassemia major
Author(s) -
PN Doctor,
Mansi Verma,
A Varaiya,
R. Merchant
Publication year - 2019
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/jpgm.jpgm_689_17
Subject(s) - medicine , salmonella typhi , osteomyelitis , thalassemia , beta thalassemia , typhoid fever , microbiology and biotechnology , virology , immunology , biochemistry , chemistry , escherichia coli , biology , gene
There have been various cases of salmonella osteomyelitis reported in sickle cell anemia. We present a case of emphysematous osteomyelitis caused by Salmonella typhi in a 29-year-old beta thalassemia major patient. Diagnosis of emphysematous osteomyelitis was confirmed by computed tomography and magnetic resonance imaging, and culture of pus drained during surgical debridement confirmed the causative microorganism, Salmonella typhi. Antimicrobials were given according to microbiological sensitivity for a period of 8 weeks. Our patient also received hyperbaric oxygen therapy. At the end of therapy, he was afebrile and laboratory parameters normalized with a residual joint deformity which developed within 3 months.