Protective effect of Rheum turkestanicum against cisplatin by reducing oxidative stress in kidney tissue | Zendy

Mohammad Taher Boroushaki | Zendy; Azar Hosseini | Zendy; Sahar Fanoudi | Zendy; Hamid Mollazadeh | Zendy; Azita Aghaei | Zendy

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Protective effect of Rheum turkestanicum against cisplatin by reducing oxidative stress in kidney tissue

Author(s) -

Mohammad Taher Boroushaki,

Azar Hosseini,

Sahar Fanoudi,

Hamid Mollazadeh,

Azita Aghaei

Publication year - 2018

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/jpbs.jpbs_9_18

Subject(s) - nephrotoxicity , creatinine , lipid peroxidation , cisplatin , oxidative stress , urinary system , kidney , pharmacology , chemistry , medicine , endocrinology , chemotherapy

Cisplatin is used as chemotherapeutic drug in the treatment of some solid tumors. It causes different side effects such as nephrotoxicity because of increasing oxidative stress and reactive oxygen species production. This study was designed to investigate the effect of Rheum turkestanicum on cisplatin-induced nephrotoxicity in rat.

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