Open AccessNew insights for consummate diagnosis and management of oral submucous fibrosis using reactive and reparative fibrotic parameter derived algorithm
Author(s) -
Ramya Ramadoss,
K Rajkumar,
V Vasanthi,
Bose Divya,
R. Vijayalakshmi,
Rajashree Padmanabhan,
S. Balakumar
Publication year - 2021
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_822_20
Subject(s) - oral submucous fibrosis , fibrosis , masson's trichrome stain , h&e stain , stain , trichrome , medicine , pathology , staining , inflammation , trichrome stain , immunohistochemistry
Reproducibility of qualitative changes in histopathological diagnosis involving narrow variation is often challenging. This study aims to characterize the histological fibrotic events in detail so as to derive an in-depth multiparametric algorithm with individually quantified histological parameters for effective monitoring of the. disease process in oral submucous fibrosis and for potential therapeutic targets for early intervention.