Determination of ethinyl estradiol and levonorgestrel in human plasma with prednisone as internal standard using ultra-performance liquid chromatography–tandem mass spectrometry | Zendy

Yahdiana Harahap | Zendy; Devina Devina | Zendy; Harmita Harmita | Zendy

Open Access

Determination of ethinyl estradiol and levonorgestrel in human plasma with prednisone as internal standard using ultra-performance liquid chromatography–tandem mass spectrometry

Author(s) -

Yahdiana Harahap,

Devina Devina,

Harmita Harmita

Publication year - 2019

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/jpbs.jpbs_68_19

Subject(s) - chromatography , chemistry , levonorgestrel , formic acid , electrospray ionization , protein precipitation , liquid chromatography–mass spectrometry , tandem mass spectrometry , high performance liquid chromatography , mass spectrometry , solid phase extraction , population , medicine , environmental health , family planning , research methodology

Ethinyl estradiol and levonorgestrel as a combination of oral contraceptive drugs have very low dosage levels; hence, a highly sensitive and selective method of using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) is needed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research