Screening of potential phytocompounds from Euclea crispa (Thunb.) leaves targeting human epidermal growth factor receptor 2 (HER2) signaling pathway | Zendy

AnofiOmotayo Tom Ashafa | Zendy; Chella Perumal Palanisamy | Zendy

Open Access

Screening of potential phytocompounds from Euclea crispa (Thunb.) leaves targeting human epidermal growth factor receptor 2 (HER2) signaling pathway

Author(s) -

AnofiOmotayo Tom Ashafa,

Chella Perumal Palanisamy

Publication year - 2019

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/jpbs.jpbs_61_18

Subject(s) - adme , pharmacology , pharmacokinetics , drug , lipinski's rule of five , epidermal growth factor receptor , chemistry , in silico , traditional medicine , medicine , receptor , biochemistry , gene

Overexpression of human epidermal growth factor receptor 2 (HER2) plays an important role in the development and progression in a variety of cancers and it is a novel therapeutic target for breast cancer and ovarian cancer. Euclea crispa ( E. crispa ) is a South African medicinal plant in the family Ebenaceae used in the management of different human diseases and disorders.

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