Open AccessImmunohistochemical Expression of the Epithelial to Mesenchymal Transition Proteins E-cadherin and β-catenin in Grades of Oral Squamous Cell Carcinoma
Author(s) -
Vijay Kumar,
Anita Panda,
K. C. Dash,
Lipsa Bhuyan,
Namita Mahapatra,
Pallavi Mishra
Publication year - 2021
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_562_20
Subject(s) - immunohistochemistry , cadherin , catenin , pathology , epithelial–mesenchymal transition , carcinogenesis , carcinoma , metastasis , cell , basal cell , medicine , biology , cancer research , wnt signaling pathway , cancer , signal transduction , genetics , biochemistry
E-Cadherin/β-Catenin protein complexes play a major role in epithelial to mesenchymal transition (EMT) and vice versa. Such types of EMT are implicated physiologically during embryonic development and pathologically in tissue fibrosis and tumorigenesis.