Open AccessRetrospective study on the pattern of off-label use of misoprostol in Tabuk, Saudi Arabia
Author(s) -
Nouf M Alharthi,
Mohannad Sahaw Alsaeed,
Mohammed Omar Alsharif,
Mohammed Ghabbash Almalki,
Wael Saeed Alshehri,
Kousalya Prabahar
Publication year - 2021
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_368_20
Subject(s) - misoprostol , medicine , medical prescription , guideline , off label use , abortion , obstetrics , retrospective cohort study , observational study , food and drug administration , pregnancy , emergency medicine , medical emergency , pharmacology , genetics , pathology , biology
Off-label drug use (OLDU) refers to the prescription of a currently available and marketed medication for a use that has never been approved by the Food and Drug Administration (FDA). Misoprostol is one of the drugs which is used off-label. This drug, authorized for the treatment or prevention of peptic ulcers and other stomach disorders, is commonly used off-label for inducing labor or intrauterine device insertion. This research focuses on identifying the percentage of morbidity and mortality by off-label use of misoprostol; classifying the most common off-label misoprostol use in Tabuk hospitals; and determining the availability of policy and procedures behind prescribing the off-label misoprostol.