Retrospective Study on the Pattern of Off-label Use of Misoprostol in Tabuk, Saudi Arabia | Zendy

Nouf M. Alharthi | Zendy; Mohannad Sahaw Alsaeed | Zendy; Mohammed Omar Alsharif | Zendy; Mohammed Ghabbash Almalki | Zendy; Wael Saeed Alshehri | Zendy; Kousalya Prabahar | Zendy

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Retrospective Study on the Pattern of Off-label Use of Misoprostol in Tabuk, Saudi Arabia

Author(s) -

Nouf M. Alharthi,

Mohannad Sahaw Alsaeed,

Mohammed Omar Alsharif,

Mohammed Ghabbash Almalki,

Wael Saeed Alshehri,

Kousalya Prabahar

Publication year - 2021

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/jpbs.jpbs_368_20

Subject(s) - misoprostol , medicine , medical prescription , guideline , off label use , abortion , retrospective cohort study , observational study , obstetrics , food and drug administration , regimen , pregnancy , emergency medicine , medical emergency , pharmacology , genetics , pathology , biology

Off-label drug use (OLDU) refers to the prescription of a currently available and marketed medication for a use that has never been approved by the Food and Drug Administration (FDA). Misoprostol is one of the drugs which is used off-label. This drug, authorized for the treatment or prevention of peptic ulcers and other stomach disorders, is commonly used off-label for inducing labor or intrauterine device insertion. This research focuses on identifying the percentage of morbidity and mortality by off-label use of misoprostol; classifying the most common off-label misoprostol use in Tabuk hospitals; and determining the availability of policy and procedures behind prescribing the off-label misoprostol.

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