Open AccessComparative evaluation of wound healing potential of manuka and acacia honey in diabetic and nondiabetic rats
Author(s) -
Rupam Gill,
Basavaraj Poojar,
Laxminarayana Kurady Bairy,
Kumar S E Praveen
Publication year - 2019
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_257_18
Subject(s) - manuka honey , medicine , wound healing , gum acacia , diabetes mellitus , methylglyoxal , traditional medicine , acacia , pharmacology , surgery , food science , chemistry , botany , biochemistry , biology , endocrinology , enzyme
Manuka honey has attracted the attention of the scientific community for its antimicrobial and antioxidant properties. The active compounds of manuka honey to which its myeloperoxidase activity inhibition is owed are methyl syringate (MSYR) and leptosin (a novel glycoside of MSYR). The non-peroxide antibacterial activity is attributed to glyoxal, 3-deoxyglucosulose, and methylglyoxal. These properties make it an inexpensive and effective topical treatment in wound management. This study has focused on the evaluation of the effect of manuka honey and acacia honey on wound healing in nondiabetic and streptozotocin-induced diabetic rats.