Open AccessSinapic acid attenuates cisplatin-induced nephrotoxicity through peroxisome proliferator-activated receptor gamma agonism in rats
Author(s) -
Harmanpreet Singh,
Thakur Gurjeet Singh,
Randhir Singh
Publication year - 2020
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_220_19
Subject(s) - nephrotoxicity , ototoxicity , cisplatin , pharmacology , kidney , toxicity , medicine , creatinine , lipid peroxidation , chemistry , oxidative stress , endocrinology , chemotherapy
The aim of this study was to investigate the involvement of peroxisome proliferator-activated receptor gamma (PPAR-γ) in renal protection offered by sinapic acid in cisplatin-induced nephrotoxicity in male rats.