Open AccessKahar method: A novel calculation method of tonicity adjustment
Author(s) -
Abd. Kakhar Umar,
Nasrul Wathoni,
Aliya Nur Hasanah,
Insan Sunan Kurniawansyah,
Marline Abdassah
Publication year - 2019
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_210_19
Subject(s) - tonicity , reliability (semiconductor) , similarity (geometry) , bioavailability , mathematics , chemistry , biomedical engineering , pharmacology , computer science , medicine , biochemistry , thermodynamics , artificial intelligence , physics , power (physics) , image (mathematics)
Hypertonic and hypotonic conditions in pharmaceutical preparations decrease the drug's absorption and bioavailability. In addition, it can cause tissue damage. There are several calculation methods to regulate hypotonic preparations. However, there are no methods that can be used to regulate hypertonic preparations without causing dose-dividing problem.