Open AccessComparative effect of curcumin and nanocurcumin on nephroprotection at cisplatin-induced rats
Author(s) -
Ni Made Dwi Sandhiutami,
Wawaimuli Arozal,
Melva Louisa,
Deni Rahmat,
Tjoeng Mandy
Publication year - 2019
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_208_19
Subject(s) - nephrotoxicity , curcumin , creatinine , blood urea nitrogen , cisplatin , pharmacology , medicine , kidney , histopathology , renal function , albumin , serum albumin , endocrinology , chemistry , chemotherapy , pathology
Cisplatin is a first-line chemotherapeutic agent for various solid tumors including ovarian and breast cancer. Thereby, it has been proven effective as an antineoplastic agent, but its clinically use is limited because of its nephrotoxicity side effect.