Open AccessHomology modeling and docking study of Shewanella-like protein phosphatase involved in the development of ookinetes in Plasmodium
Author(s) -
Sandhini Singh,
Ruchi Yadav
Publication year - 2019
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_205_18
Subject(s) - docking (animal) , biology , plasmodium falciparum , homology modeling , computational biology , ramachandran plot , macromolecular docking , malaria , genetics , protein structure , biochemistry , immunology , medicine , nursing , enzyme
Parasites of the genus Plasmodium cause a great deal of morbidity and mortality worldwide, largely in regions with limited access and indication to the tools necessary to control mosquito populations and to treat human infections of malaria. Five species of this class of eukaryotic pathogens cause different human diseases, with Plasmodium falciparum alone infecting approximately 500 million people per year and resulting in approximately one million deaths.