Open AccessImmunohistochemical detection of nerve growth factor (NGF) in follicular and plexiform ameloblastoma – A novel study
Author(s) -
Thuckanickenpalayam Ragunathan Yoithapprabhunath,
Seeni Renugadevi,
N. Ganapathy,
Janardhanam Dineshshankar,
Andamuthu Yamunadevi,
R Madhavan Nirmal
Publication year - 2020
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_185_20
Subject(s) - ameloblastoma , pathology , immunohistochemistry , odontogenic tumor , follicular phase , medicine , biology , anatomy , maxilla , odontogenic
Ameloblastoma is the second most common odontogenic tumor that holds a unique position among benign tumors due to its locally destructive and invasive nature. The differed tumor biology behind follicular and plexiform ameloblastoma is always an enigma. Nerve growth factor (NGF), a neurotrophin that plays a major role during odontogenesis, could also possibly play a role in the pathogenesis of odontogenic tumors such as ameloblastoma. With this background, the study was aimed to investigate the expression of NGF in follicular and plexiform ameloblastoma.