Open AccessDetection of salivary alkaline phosphatase levels in smokers, diabetic patients, potentially malignant diseases and oral malignant tumours
Author(s) -
A Prakash,
Prashant Nahar,
Madhusudhan Ashtekar,
Srikant Natarajan,
Rohit Singh,
Ganesh Kulkarni
Publication year - 2020
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_129_20
Subject(s) - alkaline phosphatase , medicine , malignant disease , saliva , malignant transformation , diabetes mellitus , gastroenterology , pathology , endocrinology , cancer , enzyme , chemistry , biochemistry
Alkaline phosphatase (ALP) is present in human and plays a key role in intracellular destructive processes and cellular damage. It has bicarbonate and phosphate ions, which help in buffering against acids. ALP activity is affected by smoking, which changes pH in oral environment and has harmful effects. Thus, the evaluation of ALP activity of smokers and healthy nonsmoker along with patients who were diabetic, potentially malignant, and malignant was carried out in this study.