
Apoptosis-mediated cytotoxic effect of Caralluma adscendens var. attenuata on colon (HT29) and Hepatic (HepG2) cancer cell lines
Author(s) -
M Jyothi,
Eranti Bhargav,
Chilamakuru Naresh Babu,
Kanala Somasekhar Reddy,
Bhupalam Pradeep Kumar,
Ravi Prasad Rao
Publication year - 2019
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/jpbs.jpbs_117_18
Subject(s) - cytotoxic t cell , apoptosis , traditional medicine , cancer cell lines , biology , cancer , chemistry , cancer research , pharmacology , cancer cell , medicine , biochemistry , in vitro , genetics
Caralluma adscendens var. attenuata (Wight) Grav. and Mayur., a member of Apocynaceae, is a perennial stem succulent plant with wide distribution in tropics and subtropics of the world. This plant is reported for the presence of steroids, flavonoids, saponins, triterpenes, and pregnane glycosides, and is known to have antidiabetic and antiulcerogenic properties.