Open AccessComparative analysis of the oxidative stress and antioxidant status in type II diabetics and nondiabetics: A biochemical study
Author(s) -
Archana Padmanabhan Nair,
Bindu Nair
Publication year - 2017
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_56_16
Subject(s) - saliva , malondialdehyde , lipid peroxidation , glutathione , superoxide dismutase , oxidative stress , chemistry , antioxidant , endocrinology , medicine , biochemistry , enzyme
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia along with biochemical alterations of glucose and lipid peroxidation. It produces free radicals that induce lipid peroxidation which acts as an indicator for oxidative stress in the body. The widely used assay for lipid peroxidation involves measurement of malondialdehyde (MDA). Defensive system in the body consists of antioxidant enzymes which help in scavenging free radicals. Two such antioxidant enzymes are reduced glutathione (GSH) and superoxide dismutase (SOD). In this study MDA, GSH and SOD are assessed in serum and saliva of age- and sex-matched 33 diabetics and nondiabetics.