Open AccessExpression of stem cell marker cytokeratin 19 in reduced enamel epithelium, dentigerous cyst and unicystic ameloblastoma – A comparative analysis
Author(s) -
C N V Akhila,
G Sreenath,
A Ravi Prakash,
M Rajini Kanth,
A Vikram Simha Reddy,
Sanjeev Kumar
Publication year - 2021
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_316_19
Subject(s) - dentigerous cyst , cytokeratin , ameloblastoma , pathology , enamel organ , epithelium , cyst , biology , enamel paint , immunohistochemistry , medicine , anatomy , dentistry , ameloblast , maxilla
The process of odontogenesis is complex involving epithelial-mesenchymal interactions, along with the molecular signaling pathways triggering the initiating process. The triggering factors and cells precisely involved in the pathogenesis of odontogenic cysts and tumors are unknown. There is a vast array of biomarkers used to stain different sites, thereby helpful in diagnosing and evaluating the prognosis of these cysts and tumors. Cytokeratins are the intermediate filament proteins which maintain cell integrity and alter their properties in cysts and tumors. In the following study, cytokeratin 19 expression patterns are assessed quantitatively in reduced enamel epithelium, dentigerous cyst and unicystic ameloblastoma.